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WEEKLY DIGEST | ||
Memory Loss May Not Be the Earliest Sign of Alzheimer’s | ||
Your cognitive flexibility may go first. | ||
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Memory loss is by far the most notorious symptom of Alzheimer’s disease, but it might not be the initial sign of the illness. According to a new study published in Nature Communications, there’s an even earlier tell—impaired cognitive flexibility. | ||
Cognitive flexibility is one of the brain’s executive functions governing our ability to switch between different tasks, adapt to novel situations, learn new rules, and so on. To study changes in this vital function, neuroscientists at Texas A&M University used mice genetically engineered to produce the amyloid-beta plaques associated with Alzheimer’s disease (5xFAD mice). | ||
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